产品名称
CPA5 Rabbit Polyclonal Antibody
别名
CPA5; Carboxypeptidase A5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=93979
Human Swissprot No.
Q8WXQ8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8WXQ8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74649
Mouse Swissprot No.
Q8R4H4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R4H4
免疫原
The antiserum was produced against synthesized peptide derived from human CPA5. AA range:91-140
特异性
CPA5 Polyclonal Antibody detects endogenous levels of CPA5 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]).[supplied by OMIM, Mar 2008],
组织表达
Expression is very low or not detectable.
功能
catalytic activity:Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Expression is very low or not detectable.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
