产品名称
CPA1 Rabbit Polyclonal Antibody
别名
CPA1; CPA; Carboxypeptidase A1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1357
Human Swissprot No.
P15085
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P15085/entry
Mouse Swissprot No.
Q7TPZ8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TPZ8
免疫原
The antiserum was produced against synthesized peptide derived from human Carboxypeptidase A1. AA range:301-350
特异性
CPA1 Polyclonal Antibody detects endogenous levels of CPA1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015],
功能
catalytic activity:Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,subunit:Monomer. May form a complex with proelastase 2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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