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COX7a2/3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT1079
产品名称
COX7a2/3 Rabbit Polyclonal Antibody
别名
COX7A2P2; COX7A3; COX7AL2; COX7AP2; Putative cytochrome c oxidase subunit 7A3; mitochondrial; Cytochrome c oxidase subunit VIIa 3; COX7A2; COX7AL; Cytochrome c oxidase subunit 7A2, mitochondrial; Cytochrome c oxidase subunit VIIa-liver/hear
类别
常规抗体
基因名称
COX7A2/COX7A2P2
蛋白名称
Cytochrome c oxidase subunit 7A2/3 mitochondrial
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
1347
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1347
Human Swissprot No.
O60397/P14406
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O60397/entry
Mouse Gene ID
12866
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12866
Rat Gene ID
29507
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29507
Rat Swissprot No.
P35171
Rat Swissprot Link
http://www.uniprot.org/uniprot/P35171
免疫原
The antiserum was produced against synthesized peptide derived from human COX7S/A2. AA range:1-50
特异性
COX7a2/3 Polyclonal Antibody detects endogenous levels of COX7a2/3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
预测分子量
12kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.
细胞定位
Mitochondrion inner membrane .
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using COX7S/A2 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from rat heart cells, using COX7S/A2 Antibody. The lane on the right is blocked with the synthesized peptide.

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