产品名称
COX7a2/3 Rabbit Polyclonal Antibody
别名
COX7A2P2; COX7A3; COX7AL2; COX7AP2; Putative cytochrome c oxidase subunit 7A3; mitochondrial; Cytochrome c oxidase subunit VIIa 3; COX7A2; COX7AL; Cytochrome c oxidase subunit 7A2, mitochondrial; Cytochrome c oxidase subunit VIIa-liver/hear
蛋白名称
Cytochrome c oxidase subunit 7A2/3 mitochondrial
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1347
Human Swissprot No.
O60397/P14406
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O60397/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12866
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29507
Rat Swissprot Link
http://www.uniprot.org/uniprot/P35171
免疫原
The antiserum was produced against synthesized peptide derived from human COX7S/A2. AA range:1-50
特异性
COX7a2/3 Polyclonal Antibody detects endogenous levels of COX7a2/3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.
细胞定位
Mitochondrion inner membrane .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.