BD-PT1071

COX17 Rabbit Polyclonal Antibody

COX17; Cytochrome c oxidase copper chaperone

常规抗体

COX17

Cytochrome c oxidase copper chaperone

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

10063

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10063

Q14061

http://www.uniprot.org/uniprotkb/Q14061/entry

12856

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12856

P56394

http://www.uniprot.org/uniprot/P56394

The antiserum was produced against synthesized peptide derived from human COX17. AA range:1-50

COX17 Polyclonal Antibody detects endogenous levels of COX17 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

7kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provi

Ubiquitous.

Mitochondrion intermembrane space . Cytoplasm .

Oxidative phosphorylation;

function:Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX.,similarity:Belongs to the COX17 family.,tissue specificity:Ubiquitous.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.