产品名称
CPA5 Rabbit Polyclonal Antibody
别名
CPA5; Carboxypeptidase A5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=93979
Human Swissprot No.
Q8WXQ8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8WXQ8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74649
Mouse Swissprot No.
Q8R4H4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R4H4
免疫原
The antiserum was produced against synthesized peptide derived from human CPA5. AA range:91-140
特异性
CPA5 Polyclonal Antibody detects endogenous levels of CPA5 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]).[supplied by OMIM, Mar 2008],
组织表达
Expression is very low or not detectable.
功能
catalytic activity:Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Expression is very low or not detectable.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.