产品名称
Copine 8 Rabbit Polyclonal Antibody
别名
CPNE8; Copine-8; Copine VIII
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=144402
Human Swissprot No.
Q86YQ8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86YQ8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66871
Mouse Swissprot No.
Q9DC53
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DC53
免疫原
The antiserum was produced against synthesized peptide derived from human CPNE8. AA range:11-60
特异性
Copine 8 Polyclonal Antibody detects endogenous levels of Copine 8 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
copine 8(CPNE8) Homo sapiens Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008],
细胞定位
extracellular exosome,
功能
function:May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the copine family.,similarity:Contains 1 VWFA domain.,similarity:Contains 2 C2 domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
