产品名称
Contactin 2 Rabbit Polyclonal Antibody
别名
CNTN2; AXT; TAG1; TAX1; Contactin-2; Axonal glycoprotein TAG-1; Axonin-1; Transient axonal glycoprotein 1; TAX-1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6900
Human Swissprot No.
Q02246
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q02246/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21367
Mouse Swissprot No.
Q61330
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61330
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25356
Rat Swissprot Link
http://www.uniprot.org/uniprot/P22063
免疫原
The antiserum was produced against synthesized peptide derived from human CNTN2. AA range:111-160
特异性
Contactin 2 Polyclonal Antibody detects endogenous levels of Contactin 2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the contactin family of proteins, part of the immunoglobulin superfamily of cell adhesion molecules. The encoded glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein plays a role in the proliferation, migration, and axon guidance of neurons of the developing cerebellum. A mutation in this gene may be associated with adult myoclonic epilepsy. [provided by RefSeq, Sep 2016],
组织表达
Amygdala,Brain,Placenta,Plasma,
细胞定位
Cell membrane; Lipid-anchor, GPI-anchor. Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.
信号通路
Cell adhesion molecules (CAMs);
功能
function:May play a role in the initial growth and guidance of axons. May be involved in cell adhesion.,similarity:Belongs to the immunoglobulin superfamily. Contactin family.,similarity:Contains 4 fibronectin type-III domains.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,subcellular location:Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
