产品名称
Connexin-45 Rabbit Polyclonal Antibody
别名
GJC1; GJA7; Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein
蛋白名称
Gap junction gamma-1 protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10052
Human Swissprot No.
P36383
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P36383/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14615
Mouse Swissprot No.
P28229
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P28229
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=266706
Rat Swissprot Link
http://www.uniprot.org/uniprot/A4GG66
免疫原
The antiserum was produced against synthesized peptide derived from human Connexin-45. AA range:312-361
特异性
Connexin-45 Polyclonal Antibody detects endogenous levels of Connexin-45 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
功能
function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Gamma-type subfamily.,subunit:A connexon is composed of a hexamer of connexins.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
