产品名称
Connexin 37 Rabbit Polyclonal Antibody
别名
GJA4; Gap junction alpha-4 protein; Connexin-37; Cx37
蛋白名称
Gap junction alpha-4 protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2701
Human Swissprot No.
P35212
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P35212/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14612
Mouse Swissprot No.
P28235
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P28235
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25655
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q03190
免疫原
The antiserum was produced against synthesized peptide derived from human GJA4. AA range:81-130
特异性
Connexin 37 Polyclonal Antibody detects endogenous levels of Connexin 37 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction. [provided by RefSeq, Jul 2008],
组织表达
Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
功能
function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family.,similarity:Belongs to the connexin family. Alpha-type (group II) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Expressed in multiple organs and tissues, including heart, uterus, ovary, and blood vessel endothelium.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
