产品名称
Connexin 25 Rabbit Polyclonal Antibody
别名
GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25
蛋白名称
Gap junction beta-7 protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=375519
Human Swissprot No.
Q6PEY0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6PEY0/entry
免疫原
The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70
特异性
Connexin 25 Polyclonal Antibody detects endogenous levels of Connexin 25 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],
组织表达
Weakly expressed in placenta.
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .
功能
function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Beta-type (group I) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Weakly expressed in placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
