产品名称
CNK1 Rabbit Polyclonal Antibody
别名
CNKSR1; CNK1; Connector enhancer of kinase suppressor of ras 1; Connector enhancer of KSR 1; CNK homolog protein 1; CNK1; hCNK1; Connector enhancer of KSR-like
蛋白名称
Connector enhancer of kinase suppressor of ras 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10256
Human Swissprot No.
Q969H4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q969H4/entry
免疫原
The antiserum was produced against synthesized peptide derived from human CNKR1. AA range:491-540
特异性
CNK1 Polyclonal Antibody detects endogenous levels of CNK1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein containing several motifs involved in protein-protein interaction, including PDZ, PH (Pleckstrin homology), and SAM (sterile alpha motif) domains. The encoded protein acts as a scaffold component for receptor tyrosine kinase signaling and may mediate crosstalk between different signaling pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
组织表达
Brain,Epithelium,Kidney,Liver,Neuroepithelium,Place
细胞定位
Cytoplasm . Membrane ; Peripheral membrane protein .
功能
function:May function as an adapter protein or regulator of Ras signaling pathways.,PTM:Phosphorylated on tyrosine.,similarity:Belongs to the CNKSR family.,similarity:Contains 1 CRIC domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Interacts with RHO and RALGDS.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
