产品名称
CNG-2 Rabbit Polyclonal Antibody
别名
CNGA2; CNCA; CNCA1; CNCG2; Cyclic nucleotide-gated olfactory channel; Cyclic nucleotide-gated cation channel 2; Cyclic nucleotide-gated channel alpha-2; CNG channel alpha-2; CNG-2; CNG2
蛋白名称
Cyclic nucleotide-gated olfactory channel
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1260
Human Swissprot No.
Q16280
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q16280/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12789
Mouse Swissprot No.
Q62398
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q62398
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25411
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q00195
免疫原
The antiserum was produced against synthesized peptide derived from human CNGA2. AA range:391-440
特异性
CNG-2 Polyclonal Antibody detects endogenous levels of CNG-2 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. [provided by RefSeq, Jan 2010],
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.,similarity:Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.,similarity:Contains 1 cyclic nucleotide-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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