BD-PT0974

CLLD7 Rabbit Polyclonal Antibody

RCBTB1; CLLD7; E4.5; RCC1 and BTB domain-containing protein 1; Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; Regulator of chromosome condensation and BTB domain-containing protein 1

常规抗体

RCBTB1

RCC1 and BTB domain-containing protein 1

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

55213

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55213

Q8NDN9

http://www.uniprot.org/uniprotkb/Q8NDN9/entry

71330

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71330

Q6NXM2

http://www.uniprot.org/uniprot/Q6NXM2

The antiserum was produced against synthesized peptide derived from human RCBTB1. AA range:251-300

CLLD7 Polyclonal Antibody detects endogenous levels of CLLD7 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

58kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008],

Ubiquitously expressed (PubMed:11306461, PubMed:27486781). In the retina, present in the nerve fiber layer and to a lesser extent in the inner and outer plexiform layers (at protein level) (PubMed:27486781).

Nucleus .

function:May be involved in cell cycle regulation by chromatin remodeling.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 RCC1 repeats.,tissue specificity:Ubiquitously expressed.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.