产品名称
CEP85 Rabbit Polyclonal Antibody
别名
Centrosomal protein of 85 kDa (Coiled-coil domain-containing protein 21)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.295% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/64793
Human Swissprot No.
Q6P2H3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P2H3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/70012
Mouse Swissprot No.
Q8BMK0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BMK0
免疫原
Synthesized peptide derived from human CEP85 AA range: 267-317
特异性
This antibody detects endogenous levels of CEP85 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that belongs to the centrosome-associated family of proteins. The centrosome is a subcellular organelle in the animal cell that functions as a microtubule organizing center and is involved in cell-cycle progression. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
组织表达
Hepatoma,Placenta,Retinoblastoma,Testis,
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Nucleus, nucleolus . Localizes to centrosomes and nucleolus in interphase. Upon entry into mitosis, relocates from nucleolus and accumulates at spindle poles (PubMed:21399614). Associated with the pericentriolar material. Localizes to centrosomes at a low level in G1 phase and a slightly increased level in S phase, with gradually elevated levels during G2 phase. The levels at centrosomes further increase at G2/M, reaching a peak at spindle poles at early mitotic stages and remain high until the end of anaphase (PubMed:26220856). .
功能
similarity:Belongs to the CCDC21 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
