产品名称
CIP29 Rabbit Polyclonal Antibody
别名
SARNP; HCC1; HSPC316; SAP domain-containing ribonucleoprotein; Cytokine-induced protein of 29 kDa; Nuclear protein Hcc-1; Proliferation-associated cytokine-inducible protein CIP29
蛋白名称
SAP domain-containing ribonucleoprotein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84324
Human Swissprot No.
P82979
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P82979/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66118
Mouse Swissprot No.
Q9D1J3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D1J3
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362819
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q498U4
免疫原
The antiserum was produced against synthesized peptide derived from human HCC1. AA range:147-196
特异性
CIP29 Polyclonal Antibody detects endogenous levels of CIP29 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
组织表达
Low expression in spleen, liver, pancreas, testis, thymus, heart, and kidney. Increased levels are seen in hepatocellular carcinoma and pancreatic adenocarcinoma.
细胞定位
Nucleus. Nucleus speckle.
功能
transcription,?regulation of transcription, DNA-dependent,?regulation of translation,?posttranscriptional regulation of gene expression,?regulation of cellular protein metabolic process,?regulation of transcription,?regulation of RNA metabolic process,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
