BD-PT0897

ChemR23 Rabbit Polyclonal Antibody

CMKLR1; CHEMR23; DEZ; Chemokine-like receptor 1; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ

常规抗体

CMKLR1

Chemokine-like receptor 1

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1240

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1240

Q99788

http://www.uniprot.org/uniprotkb/Q99788/entry

14747

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14747

P97468

http://www.uniprot.org/uniprot/P97468

O35786

http://www.uniprot.org/uniprot/O35786

The antiserum was produced against synthesized peptide derived from human CMKLR1. AA range:221-270

ChemR23 Polyclonal Antibody detects endogenous levels of ChemR23 protein.

WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.

42kD

-20°C/1 year

Polyclonal, Rabbit,IgG

developmental stage:Expressed during bone development.,function:Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.,

Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow and fetal liver. Among leukocyte populations abundant expression in monocyte-derived macrophage and immature dendritic cells (DCs). High expression in blood monocytes and low levels in polymorphonuclear cells and T-cells. Expressed on endothelial cells. Highly expressed in differentiating adipocytes.

Cell membrane ; Multi-pass membrane protein . Internalizes efficiently in response to RARRES2. .

developmental stage:Expressed during bone development.,function:Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.