产品名称
Cerebellin 4 Rabbit Polyclonal Antibody
别名
CBLN4; CBLNL1; Cerebellin-4; Cerebellin-like glycoprotein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140689
Human Swissprot No.
Q9NTU7
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NTU7/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228942
Mouse Swissprot No.
Q8BME9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BME9
免疫原
The antiserum was produced against synthesized peptide derived from human CBLN4. AA range:141-190
特异性
Cerebellin 4 Polyclonal Antibody detects endogenous levels of Cerebellin 4 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor. [provided by RefSeq, Aug 2012],
细胞定位
Secreted . Cell junction, synapse . Detected at GABAergic synapses. .
功能
function:May be involved in synaptic functions in the CNS. Can enable ER export and secretion of CBLN3.,similarity:Contains 1 C1q domain.,subunit:Homohexamer; disulfide-linked homotrimers. The trimers are assembled via the globular C1q domains. The trimers associate via N-terminal cysteine residues to form disulfide-linked hexamers. May interact with CBLN1, CBLN2 and CBLN3.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
