产品名称
Cep97 Rabbit Polyclonal Antibody
别名
CEP97; LRRIQ2; Centrosomal protein of 97 kDa; Cep97; Leucine-rich repeat and IQ domain-containing protein 2
蛋白名称
Centrosomal protein of 97 kDa
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79598
Human Swissprot No.
Q8IW35
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8IW35/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74201
Mouse Swissprot No.
Q9CZ62
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CZ62
免疫原
The antiserum was produced against synthesized peptide derived from human CEP97. AA range:581-630
特异性
Cep97 Polyclonal Antibody detects endogenous levels of Cep97 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IQ domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subunit:Interacts with CALM1 and CEP110.,
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Recruited at the distal end of the mother centriole by MPHOSPH9. .
功能
function:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IQ domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subunit:Interacts with CALM1 and CEP110.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
