产品名称
CEP152 Rabbit Polyclonal Antibody
别名
CEP152; KIAA0912; Centrosomal protein of 152 kDa; Cep152
蛋白名称
Centrosomal protein of 152 kDa
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22995
Human Swissprot No.
O94986
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O94986/entry
免疫原
The antiserum was produced against synthesized peptide derived from human CEP152. AA range:841-890
特异性
CEP152 Polyclonal Antibody detects endogenous levels of CEP152 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
centrosomal protein 152(CEP152) Homo sapiens This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010],
组织表达
Bladder,Brain,Heart,Lung,Testis,
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Colocalizes with CDK5RAP2, WDR62 and CEP63 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (PubMed:21983783, PubMed:26297806). Localizes to the deuterosome (By similarity). Localizes to pericentriolar material (PCM) (PubMed:26337392). .
功能
sequence caution:Contaminating sequence. Potential poly-A sequence.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
