产品名称
Cdx2 Rabbit Polyclonal Antibody
别名
CDX2; CDX3; Homeobox protein CDX-2; CDX-3; Caudal-type homeobox protein 2
蛋白名称
Homeobox protein CDX-2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1045
Human Swissprot No.
Q99626
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q99626/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12591
Mouse Swissprot No.
P43241
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P43241
免疫原
The antiserum was produced against synthesized peptide derived from human CDX2. AA range:249-298
特异性
Cdx2 Polyclonal Antibody detects endogenous levels of Cdx2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012],
组织表达
Detected in small intestine, colon and pancreas.
功能
function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
