产品名称
Cdk10 Rabbit Polyclonal Antibody
别名
CDK10; Cyclin-dependent kinase 10; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE
蛋白名称
Cyclin-dependent kinase 10
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8558
Human Swissprot No.
Q15131
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15131/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=234854
Mouse Swissprot No.
Q3UMM4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UMM4
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=361434
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q4KM47
免疫原
The antiserum was produced against synthesized peptide derived from human CDK10. AA range:51-100
特异性
Cdk10 Polyclonal Antibody detects endogenous levels of Cdk10 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
组织表达
Brain,Colon,Kidney,Lung,
细胞定位
Cytoplasm, cytoskeleton, cilium basal body .
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.