BD-PT0818

Cdc7 Rabbit Polyclonal Antibody

CDC7; CDC7L1; Cell division cycle 7-related protein kinase; CDC7-related kinase; HsCdc7; huCdc7

常规抗体

CDC7

Cell division cycle 7-related protein kinase

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

8317

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8317

O00311

http://www.uniprot.org/uniprotkb/O00311/entry

Q9Z0H0

http://www.uniprot.org/uniprot/Q9Z0H0

The antiserum was produced against synthesized peptide derived from human CDC7. AA range:1-50

Cdc7 Polyclonal Antibody detects endogenous levels of Cdc7 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

70kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008],

Brain,Embryonal rhabdomyosarcoma,Liver,Testis,

Nucleus.

Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;

alternative products:A number of isoforms may be produced,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Forms a complex with either DBF4/DBF4A or DBF4B, leading to the activation of the kinase activity.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.