BD-PT0810

Cdc42EP4 Rabbit Polyclonal Antibody

CDC42EP4; BORG4; CEP4; Cdc42 effector protein 4; Binder of Rho GTPases 4

常规抗体

CDC42EP4

Cdc42 effector protein 4

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

23580

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23580

Q9H3Q1

http://www.uniprot.org/uniprotkb/Q9H3Q1/entry

Q9JM96

http://www.uniprot.org/uniprot/Q9JM96

The antiserum was produced against synthesized peptide derived from human BORG4. AA range:201-250

Cdc42EP4 Polyclonal Antibody detects endogenous levels of Cdc42EP4 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

36kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008],

Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.

Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.

function:Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with CDC42 and RHOQ, in a GTP-dependent manner.,tissue specificity:Not detected in any of the adult tissues tested. May be expressed only in fetal or embryonic tissues.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.