BD-PT0807

Cdc40 Rabbit Polyclonal Antibody

CDC40; EHB3; PRP17; PRPF17; Pre-mRNA-processing factor 17; Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; PRP17 homolog; hPRP17

常规抗体

CDC40

Pre-mRNA-processing factor 17

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

51362

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51362

O60508

http://www.uniprot.org/uniprotkb/O60508/entry

71713

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71713

Q9DC48

http://www.uniprot.org/uniprot/Q9DC48

The antiserum was produced against synthesized peptide derived from human CDC40. AA range:179-228

Cdc40 Polyclonal Antibody detects endogenous levels of Cdc40 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

66kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008],

Brain,Cervix carcinoma,Colon,Colon epithelium,Epithelium,Trachea,

Nucleus . Nucleus speckle .

Spliceosome;

function:Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.,similarity:Contains 7 WD repeats.,subunit:Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.