产品名称
SOX5 Rabbit Polyclonal Antibody
别名
Transcription factor SOX-5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.303% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/6660
Human Swissprot No.
P35711
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P35711/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20678
Mouse Swissprot No.
P35710
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P35710
免疫原
Synthesized peptide derived from human SOX5 AA range: 43-93
特异性
This antibody detects endogenous levels of SOX5 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
组织表达
Brain,Fetal heart,Heart,Liver,Testis,
功能
function:Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.,similarity:Contains 1 HMG box DNA-binding domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
