BD-PT0746-CD2BP2 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

CD2BP2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT0746

产品名称

CD2BP2 Rabbit Polyclonal Antibody

别名

CD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2

类别

常规抗体

基因名称

CD2BP2

蛋白名称

CD2 antigen cytoplasmic tail-binding protein 2

推荐应用

反应种属

Human,Monkey

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

10421

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10421

Human Swissprot No.

O95400

Human Swissprot Link

http://www.uniprot.org/uniprotkb/O95400/entry

Mouse Swissprot No.

Q9CWK3

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q9CWK3

免疫原

The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150

特异性

CD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

预测分子量

50kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],

组织表达

Aorta,Brain,Epithelium,Liver,Lung,

细胞定位

Cytoplasm. Nucleus. Predominantly nuclear.

功能

similarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from COS7 cells, using CD2 Tail-binding Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HeLa cells using CD2 Tail-binding antibody.

Western Blot analysis of various cells using CD2BP2 Polyclonal Antibody diluted at 1：1000

Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.