产品名称
CCS Rabbit Polyclonal Antibody
别名
CCS; Copper chaperone for superoxide dismutase; Superoxide dismutase copper chaperone
蛋白名称
Copper chaperone for superoxide dismutase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9973
Human Swissprot No.
O14618
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O14618/entry
Mouse Swissprot No.
Q9WU84
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WU84
免疫原
The antiserum was produced against synthesized peptide derived from human CCS. AA range:225-274
特异性
CCS Polyclonal Antibody detects endogenous levels of CCS protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008],
信号通路
Amyotrophic lateral sclerosis (ALS);
功能
cofactor:Binds 1 zinc ion per subunit.,cofactor:Binds 2 copper ions per subunit.,function:Delivers copper to copper zinc superoxide dismutase (SOD1).,similarity:Contains 1 HMA domain.,similarity:In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.,subunit:Homodimer, and heterodimer with SOD1.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
