产品名称
CCDC102B Rabbit Polyclonal Antibody
别名
CCDC102B; C18orf14; Coiled-coil domain-containing protein 102B
蛋白名称
Coiled-coil domain-containing protein 102B
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79839
Human Swissprot No.
Q68D86
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q68D86/entry
免疫原
The antiserum was produced against synthesized peptide derived from human CCDC102B. AA range:81-130
特异性
CCDC102B Polyclonal Antibody detects endogenous levels of CCDC102B protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
CCDC102B (coiled-coil domain containing 102B), also known as AN, ACY1L or HsT1731, is a 513 amino acid protein that exists as three alternatively spliced isoforms. Widely expressed and found in multiple CNV (copy-number variant) regions, CCDC102B contains the deletion breakpoint of a maternally inherited deletion, which is 2.7?Mb in size, and maps to human chromosome 18q22.1. CCDC102B may play a role in the pathogenesis of diaphragmatic hernia, microphthalmia, colorectal carcinoma and schizophrenia. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Translocation between chromosomes 18 and 14 is the most common translocation in cancers and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18.
组织表达
Lung,Salivary gland,Testis,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
