产品名称
OSBL1 Rabbit Polyclonal Antibody
别名
Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1)
基因名称
OSBPL1A ORP1 OSBP8 OSBPL1 OSBPL1B
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.209% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/114876
Human Swissprot No.
Q9BXW6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BXW6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/64291
Mouse Swissprot No.
Q91XL9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91XL9
Rat Gene Link
https://www.uniprot.org/uniprot/259221
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K4M9
免疫原
Synthesized peptide derived from human OSBL1 AA range: 229-279
特异性
This antibody detects endogenous levels of OSBL1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008],
组织表达
Bone,Brain,Embryo,Epithelium,Kidney,Pancreas,Testicle,
细胞定位
Late endosome . Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes.
功能
function:Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate.,similarity:Belongs to the OSBP family.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,subunit:Interacts with VAPA.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
