产品名称
FAM5C Rabbit Polyclonal Antibody
别名
Protein FAM5C (DBCCR1-like protein 1)
基因名称
FAM5C DBCCR1L DBCCR1L1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.314% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/339479
Human Swissprot No.
Q76B58
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q76B58/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/215378
Mouse Swissprot No.
Q499E0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q499E0
Rat Gene Link
https://www.uniprot.org/uniprot/286901
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q8K1M7
免疫原
Synthesized peptide derived from human FAM5C AA range: 503-553
特异性
This antibody detects endogenous levels of FAM5C at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],
组织表达
Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues.
细胞定位
Secreted . Mitochondrion .
功能
similarity:Belongs to the FAM5 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
