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Casein Kinase I α1/1L Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT0642
产品名称
Casein Kinase I α1/1L Rabbit Polyclonal Antibody
别名
CSNK1A1L; Casein kinase I isoform alpha-like; CKI-alpha-like; CK1; CSNK1A1; Casein kinase I isoform alpha; CKI-alpha; CK1
类别
常规抗体
基因名称
CSNK1A1/CSNK1A1L
蛋白名称
Casein kinase I isoform alpha/Casein kinase I isoform alpha-like
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
122011/1452
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=122011
Human Swissprot No.
Q8N752/P48729
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8N752/entry
Rat Gene ID
113927
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=113927
Rat Swissprot No.
P97633
Rat Swissprot Link
http://www.uniprot.org/uniprot/P97633
免疫原
The antiserum was produced against synthesized peptide derived from human CKI-alpha1/L. AA range:141-190
特异性
Casein Kinase I α1/1L Polyclonal Antibody detects endogenous levels of Casein Kinase I α1/1L protein.
稀释度
WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
预测分子量
30kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,
组织表达
Testis,
细胞定位
Cytoplasm .
信号通路
WNT;WNT-T CELLHedgehog;
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of A549 cells, using CKI-alpha1/L Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CKI-alpha1/L Antibody. The picture on the right is blocked with the synthesized peptide.

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