产品名称
Cardiotrophin-1 Rabbit Polyclonal Antibody
别名
CTF1; Cardiotrophin-1; CT-1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1489
Human Swissprot No.
Q16619
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q16619/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=13019
Mouse Swissprot No.
Q60753
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q60753
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29201
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q63086
免疫原
The antiserum was produced against synthesized peptide derived from human Cardiotrophin-1. AA range:31-80
特异性
Cardiotrophin-1 Polyclonal Antibody detects endogenous levels of Cardiotrophin-1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
组织表达
Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes.
信号通路
Cytokine-cytokine receptor interaction;Jak_STAT;
功能
function:Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.,similarity:Belongs to the IL-6 superfamily.,tissue specificity:Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
