产品名称
Carbonyl Reductase 3 Rabbit Polyclonal Antibody
别名
CBR3; Carbonyl reductase [NADPH] 3; NADPH-dependent carbonyl reductase 3
蛋白名称
Carbonyl reductase [NADPH] 3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=874
Human Swissprot No.
O75828
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O75828/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=109857
Mouse Swissprot No.
Q8K354
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K354
免疫原
The antiserum was produced against synthesized peptide derived from human CBR3. AA range:151-200
特异性
Carbonyl Reductase 3 Polyclonal Antibody detects endogenous levels of Carbonyl Reductase 3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008],
组织表达
Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis.
信号通路
Arachidonic acid metabolism;
功能
catalytic activity:R-CHOH-R' + NADP(+) = R-CO-R' + NADPH.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
