产品名称
Calpain 12 Rabbit Polyclonal Antibody
别名
CAPN12; Calpain-12; Calcium-activated neutral proteinase 12; CANP 12
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=147968
Human Swissprot No.
Q6ZSI9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6ZSI9/entry
Mouse Swissprot No.
Q9ER56
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9ER56
免疫原
The antiserum was produced against synthesized peptide derived from human CAPN12. AA range:221-270
特异性
Calpain 12 Polyclonal Antibody detects endogenous levels of Calpain 12 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012],
细胞定位
intracellular,cytoplasm,
功能
catalytic activity:Broad endopeptidase specificity.,function:Calcium-regulated non-lysosomal thiol-protease.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 1 EF-hand domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.