产品名称
Cadherin-26 Rabbit Polyclonal Antibody
别名
CDH26; Cadherin-like protein 26; Cadherin-like protein VR20
蛋白名称
Cadherin-like protein 26
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60437
Human Swissprot No.
Q8IXH8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8IXH8/entry
Mouse Swissprot No.
P59862
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P59862
免疫原
The antiserum was produced against synthesized peptide derived from human CDH26. AA range:11-60
特异性
Cadherin-26 Polyclonal Antibody detects endogenous levels of Cadherin-26 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
Cadherins are a family of adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization and migration. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This gene encodes a cadherin domain-containing protein whose specific function has not yet been determined. Alternative splicing occurs at this locus and two transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jul 2008],
组织表达
Expressed by epithelial cells of gastrointestinal tissue.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 4 cadherin domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
