产品名称
ZER1 Rabbit Polyclonal Antibody
别名
Protein zer-1 homolog (Hzyg) (Zyg-11 homolog B-like protein)
基因名称
ZER1 C9orf60 ZYG ZYG11BL
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.318% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10444
Human Swissprot No.
Q7Z7L7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q7Z7L7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/227693
Mouse Swissprot No.
Q80ZJ6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q80ZJ6
免疫原
Synthesized peptide derived from human ZER1 AA range: 388-438
特异性
This antibody detects endogenous levels of ZER1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis. The encoded protein contains three leucine-rich repeat motifs. [provided by RefSeq, Nov 2012],
组织表达
Expressed in testis, spermatocytes and spermatids (at protein level). Expressed in spermatocytes, spermatids, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.
细胞定位
Cul2-RING ubiquitin ligase complex,
功能
function:Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZER1-CUL2-Elongin BC.,similarity:Belongs to the zyg-11 family.,similarity:Contains 3 LRR (leucine-rich) repeats.,similarity:Contains 5 ARM repeats.,subunit:Interacts with the TCEB1-TCEB2/Elongin BC complex. Part of an E3 ubiquitin ligase complex including ZER1, CUL2 and Elongin BC.,tissue specificity:Expressed in testis, spermatocytes and spermatides (at protein level). Expressed in spermatocytes, spermatides, prostate, skeletal muscle, ovary, small intestine, heart, brain and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
