产品名称
Cadherin-22 Rabbit Polyclonal Antibody
别名
CDH22; C20orf25; Cadherin-22; Pituitary and brain cadherin; PB-cadherin
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=64405
Human Swissprot No.
Q9UJ99
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UJ99/entry
Mouse Swissprot No.
Q9WTP5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WTP5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29182
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q63315
免疫原
The antiserum was produced against synthesized peptide derived from human CDH22. AA range:111-160
特异性
Cadherin-22 Polyclonal Antibody detects endogenous levels of Cadherin-22 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues.,similarity:Contains 5 cadherin domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
