产品名称
Cadherin-19 Rabbit Polyclonal Antibody
别名
CDH19; CDH7L2; Cadherin-19
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=28513
Human Swissprot No.
Q9H159
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H159/entry
免疫原
The antiserum was produced against synthesized peptide derived from human CDH19. AA range:371-420
特异性
Cadherin-19 Polyclonal Antibody detects endogenous levels of Cadherin-19 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is one of three related type II cadherin genes situated in a cluster on chromosome 18. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats. Loss of cadherins may be associated with cancer formation. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Aug 2012],
组织表达
Expressed in many tissues, with the exception of uterus.
细胞定位
Cell membrane; Single-pass type I membrane protein.
功能
function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed in many tissues, with the exception of uterus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
