BD-PT0594

Cadherin-16 Rabbit Polyclonal Antibody

CDH16; Cadherin-16; Kidney-specific cadherin; Ksp-cadherin

常规抗体

CDH16

Cadherin-16

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

1014

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1014

O75309

http://www.uniprot.org/uniprotkb/O75309/entry

O88338

http://www.uniprot.org/uniprot/O88338

The antiserum was produced against synthesized peptide derived from human CDH16. AA range:780-829

Cadherin-16 Polyclonal Antibody detects endogenous levels of Cadherin-16 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

90kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],

Kidney specific.

Cell membrane ; Single-pass type I membrane protein .

Adherens_Junction

function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 6 cadherin domains.,tissue specificity:Kidney specific.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.