产品名称
GOGA1 Rabbit Polyclonal Antibody
别名
Golgin subfamily A member 1 (Golgin-97)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.320% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/2800
Human Swissprot No.
Q92805
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92805/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/76899
Mouse Swissprot No.
Q9CW79
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CW79
免疫原
Synthesized peptide derived from human GOGA1 AA range: 169-219
特异性
This antibody detects endogenous levels of GOGA1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein is associated with Sjogren's syndrome. [provided by RefSeq, Feb 2010],
组织表达
Brain,Cervix carcinoma,Testis,
细胞定位
Golgi apparatus membrane ; Peripheral membrane protein . Golgi apparatus, trans-Golgi network membrane . Cytoplasmic vesicle, secretory vesicle, acrosome .
功能
disease:Antibodies against GOLGA1 are present in sera from patients with Sjoegren syndrome. Sera from patients with Sjoegren syndrome often contain antibodies that react with normal components of the Golgi complex.,domain:Extended rod-like protein with coiled-coil domains.,function:Probably involved in maintaining Golgi structure.,similarity:Contains 1 GRIP domain.,subunit:Binds RAB6A.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
