产品名称
C/EBP δ/ε Rabbit Polyclonal Antibody
别名
CEBPD; CCAAT/enhancer-binding protein delta; C/EBP delta; Nuclear factor NF-IL6-beta; NF-IL6-beta; CEBPE; CCAAT/enhancer-binding protein epsilon; C/EBP epsilon
蛋白名称
CCAAT/enhancer-binding protein delta/epsilon
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1052
Human Swissprot No.
P49716/Q15744
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P49716/entry
Mouse Gene ID
12609/110794
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12609
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25695
Rat Swissprot No.
Q03484/P56261
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q03484
免疫原
The antiserum was produced against synthesized peptide derived from human CEBPD/E. AA range:171-220
特异性
C/EBP δ/ε Polyclonal Antibody detects endogenous levels of C/EBP δ/ε protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010],
组织表达
Cerebellum,Placenta,
功能
function:C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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