产品名称
BTF Rabbit Polyclonal Antibody
别名
BCLAF1; BTF; KIAA0164; Bcl-2-associated transcription factor 1; Btf
蛋白名称
Bcl-2-associated transcription factor 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9774
Human Swissprot No.
Q9NYF8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NYF8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72567
Mouse Swissprot No.
Q8K019
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K019
免疫原
The antiserum was produced against synthesized peptide derived from human BCLAF1. AA range:281-330
特异性
BTF Polyclonal Antibody detects endogenous levels of BTF protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Nucleus. Nucleus speckle . Nucleus, nucleoplasm .
功能
function:Death-promoting transcriptional repressor.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA.,tissue specificity:Ubiquitous.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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