产品名称
BRS-3 Rabbit Polyclonal Antibody
别名
BRS3; Bombesin receptor subtype-3; BRS-3
蛋白名称
Bombesin receptor subtype-3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=680
Human Swissprot No.
P32247
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P32247/entry
Mouse Swissprot No.
O54798
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O54798
免疫原
The antiserum was produced against synthesized peptide derived from human BRS3. AA range:161-210
特异性
BRS-3 Polyclonal Antibody detects endogenous levels of BRS-3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011],
组织表达
In germ cells in testis. Lung carcinoma cells.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:In germ cells in testis. Lung carcinoma cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
