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BRS-3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT0533
产品名称
BRS-3 Rabbit Polyclonal Antibody
别名
BRS3; Bombesin receptor subtype-3; BRS-3
类别
常规抗体
基因名称
BRS3
蛋白名称
Bombesin receptor subtype-3
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
680
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=680
Human Swissprot No.
P32247
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P32247/entry
Mouse Swissprot No.
O54798
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O54798
免疫原
The antiserum was produced against synthesized peptide derived from human BRS3. AA range:161-210
特异性
BRS-3 Polyclonal Antibody detects endogenous levels of BRS-3 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
预测分子量
44kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011],
组织表达
In germ cells in testis. Lung carcinoma cells.
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Neuroactive ligand-receptor interaction;
功能
function:Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:In germ cells in testis. Lung carcinoma cells.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of A549 cells, using BRS3 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HUVEC cells, using BRS3 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HT-29 cells using BRS3 antibody.

Western Blot analysis of various cells using BRS-3 Polyclonal Antibody

Western Blot analysis of HuvEc cells using BRS-3 Polyclonal Antibody

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