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BRD3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT0522
产品名称
BRD3 Rabbit Polyclonal Antibody
别名
BRD3; KIAA0043; RING3L; Bromodomain-containing protein 3; RING3-like protein
类别
常规抗体
基因名称
BRD3
蛋白名称
Bromodomain-containing protein 3
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
8019
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8019
Human Swissprot No.
Q15059
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15059/entry
Mouse Gene ID
67382
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=67382
Mouse Swissprot No.
Q8K2F0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K2F0
免疫原
The antiserum was produced against synthesized peptide derived from human BRD3. AA range:611-660
特异性
BRD3 Polyclonal Antibody detects endogenous levels of BRD3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
预测分子量
90kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008],
组织表达
Ubiquitous.
细胞定位
Nucleus . Detected on chromatin. .
功能
disease:A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.,similarity:Contains 2 bromo domains.,tissue specificity:Ubiquitous.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from A549 cells, using BRD3 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using BRD3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

Western Blot analysis of A549 cells using BRD3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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