产品名称
AF1L1 Rabbit Polyclonal Antibody
别名
Actin filament-associated protein 1-like 1 (AFAP1-like protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.325% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/134265
Human Swissprot No.
Q8TED9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8TED9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/106877
Mouse Swissprot No.
Q8BZI0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BZI0
Rat Gene Link
https://www.uniprot.org/uniprot/291565
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/D4AB98
免疫原
Synthesized peptide derived from human AF1L1 AA range: 180-230
特异性
This antibody detects endogenous levels of AF1L1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Expressed in breast, colon and brain. In all 3 tissues, expressed in the microvasculature (at protein level). In addition, in the breast, found in the contractile myoepithelial cell layer which surrounds the breast ducts (at protein level). In the colon, expressed in the mucous membrane and colonic crypts and in the smooth muscle cell layer which provide movement of the colon (at protein level). In the cerebellum, localized around the Purkinje neurons and the granule cells of the granular layer, but not inside cell bodies (at protein level). Outside of the cerebellar cortex, expressed in glial cells (at protein level). Highly expressed away from the cell bodies within the dentate nucleus (at protein level).
细胞定位
Cytoplasm . Cell projection, podosome . Cell projection, invadopodium . Cytoplasm, cytoskeleton, stress fiber .
功能
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 PH domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
