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BMP-5 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT0501
产品名称
BMP-5 Rabbit Polyclonal Antibody
别名
BMP5; Bone morphogenetic protein 5; BMP-5
类别
常规抗体
基因名称
BMP5
蛋白名称
Bone morphogenetic protein 5
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
653
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=653
Human Swissprot No.
P22003
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P22003/entry
Mouse Gene ID
12160
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12160
Mouse Swissprot No.
P49003
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P49003
免疫原
The antiserum was produced against synthesized peptide derived from human BMP-5. AA range:114-163
特异性
BMP-5 Polyclonal Antibody detects endogenous levels of BMP-5 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
预测分子量
52kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Polymorphisms in this gene may be associated with osteoarthritis in human patients. This gene is differentially regulated in multiple human cancers. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016],
组织表达
Expressed in the lung and liver.
细胞定位
Secreted.
信号通路
Hedgehog;TGF-beta;
功能
function:Induces cartilage and bone formation.,online information:Bone morphogenetic protein 5 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed in the lung and liver.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of BMP-5 antibody in paraffin-embedded human heart tissue.

Western blot analysis of lysate from HUVEC cells, using BMP-5 antibody.

Western Blot analysis of various cells using BMP-5 Polyclonal Antibody diluted at 1:1000

Western Blot analysis of HeLa cells using BMP-5 Polyclonal Antibody diluted at 1:1000

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