产品名称
BCA3 Rabbit Polyclonal Antibody
别名
AKIP1; BCA3; C11orf17; A-kinase-interacting protein 1; Breast cancer-associated gene 3 protein; PKA-interacting protein; Proline-rich protein BCA3
蛋白名称
A-kinase-interacting protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56672
Human Swissprot No.
Q9NQ31
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NQ31/entry
Mouse Swissprot No.
Q9JJR5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JJR5
免疫原
The antiserum was produced against synthesized peptide derived from human BCA3. AA range:111-160
特异性
BCA3 Polyclonal Antibody detects endogenous levels of BCA3 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
组织表达
Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.
细胞定位
Nucleus . Locates to punctate spots.
功能
subcellular location:Locates to punctate spots.,subunit:Interacts with PRKACA.,tissue specificity:Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up-regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
