产品名称
BACH1 Rabbit Polyclonal Antibody
别名
BACH1; Transcription regulator protein BACH1; BTB and CNC homolog 1; HA2303
蛋白名称
Transcription regulator protein BACH1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=571
Human Swissprot No.
O14867
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O14867/entry
Mouse Swissprot No.
P97302
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P97302
免疫原
The antiserum was produced against synthesized peptide derived from human BACH1. AA range:131-180
特异性
BACH1 Polyclonal Antibody detects endogenous levels of BACH1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009],
组织表达
Epithelium,Placenta,Trachea,
功能
function:Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
