产品名称
AVP Receptor V3 Rabbit Polyclonal Antibody
别名
AVPR1B; AVPR3; VPR3; Vasopressin V1b receptor; V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor
蛋白名称
Vasopressin V1b receptor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=553
Human Swissprot No.
P47901
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P47901/entry
Mouse Swissprot No.
Q9WU02
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9WU02
免疫原
The antiserum was produced against synthesized peptide derived from human AVPR1B. AA range:275-324
特异性
AVP Receptor V3 Polyclonal Antibody detects endogenous levels of AVP Receptor V3 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],
组织表达
Lung carcinoma,Pituitary,
细胞定位
Cell membrane ; Multi-pass membrane protein .
信号通路
Calcium;Neuroactive ligand-receptor interaction;Vascular smooth muscle contraction;
功能
function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
